St. Eustache‘s history began at Baie St. Paul when Father George-Antoine Belcourt established a mission there in 1834, at the corner of Highway #26 and Route 248. However, due to numerous floodings, the prosperous village of Baie St. Paul was moved in 1888 from the north side of the Assiniboine River to its present site between Highway #26 and the Trans-Canada Highway. The name St. Eustache was chosen because the parishioners, many of them Metis, were hunters and St. Eustache is the patron saint of hunters.

The church carillon at St. Eustache is the largest carillon in all of western Canada. The bells were purchased in France in 1928, and were first installed in the steeple. In 1990 they were installed into the present tower in front of the church. Their total weight is 5500 pounds.